For 10 years, a 67-year-old patient with bipolar disorder ha…
For 10 years, a 67-year-old patient with bipolar disorder has been treated with Eskalith (lithium) 900mg daily. When oral hydrochlorothiazide (HCTZ) 12.5mg daily is added for hypertension, the patient develops nausea, vomiting, ataxia, and muscle weakness. The patient’s serum lithium level is 2.1 mEq/L. The interaction of the lithium and the thiazide diuretic has induced