Muscle hypertrophy as a result of resistance training is an…

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Muscle hypertrоphy аs а result оf resistаnce training is an example оf which principle of allostasis?

CASE STUDY: CONNECTIVE TISSUE Nаthаn Drаke is a 20-year-оld cоllege basketball star. At his mоst recent annual physical exam, the university physician detected a barely noticeable heart murmur. Nathan reported feeling fine, with no respiratory difficulties or other cardiovascular symptoms. Upon further analysis, however, the physician noticed some other skeletomuscular symptoms. Nathan's wingspan was longer than his height (usually a 1:1 ratio) and his fingers were long and thin. He was also able to bend his thumb back far enough to reach his radius. Nathan didn't complain of any visual symptoms but had previously been diagnosed with myopia. The physician recommended that Nathan have follow-up appointments with a cardiologist and an ophthalmologist. After receiving confirmation from the cardiologist of a mitral valve prolapse, Nathan's physician diagnosed him with Marfan Syndrome. Marfan syndrome is an inherited disorder that affects the connective tissues of the heart, blood vessels, eyes, bones, lungs, and covering of spinal cord. Individuals with Marfan syndrome are often tall and thin with long limbs and flexible joints. A mutation in the FBNl gene causes a reduced amount of fibrillin to be produced, which is a necessary component of elastic fibers in connective tissue. This lack of elasticity causes the stretching of joints and tissues. The most lethal symptoms of Marfan syndrome involve the heart. Stretching within the walls of the heart can cause the aorta to tear. In Nathan's case, the mitral valve lost elasticity and became floppy, causing it to no longer close tightly. Nathan's myopia (near-sightedness caused by an elongation of the eye) is a symptom of Marfan syndrome, as well. The lens of the eye can become dislocated, requiring surgery. There is no cure for Marfan syndrome, although the symptoms can be treated. Heart and eye surgery can repair affected structures and beta-blockers, which cause the heart to beat with less force, can reduce the strain on the heart and blood vessels. Individuals with Marfan syndrome should also discuss their diagnosis with relatives, as there is a high likelihood of other family members with some form of the disease. Question: What structures in the connective tissues are affected by Marfan syndrome?

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