A family adopts several children from a TB endemic country….

A family adopts several children from a TB endemic country.  They refuse any vaccinations on religious grounds, and the children were unvaccinated before immigrating. All the children are home schooled.  One of the older children, a teenager, develops a cough and is taken to the clinic.  The physician diagnosis active TB and notifies the health department.  What is the most appropriate course of action?