The sequence 5’…UGAGCUCGUUGUAUU…3′ is changed to 5′ UGAGACUCGUUGUAUU…3′. What would be the affect on the amino acid sequence?

A tRNA anticodon is 5’ CUG 3’. What amino acid does it carry?

What type of mutation is this in Question 25?

Describe the Central Dogma of Genetics/Biology and include in this description how mutations lead to genetic diseases and disorders. 

Match each of the following genetic tests with the correct description. 

What are some of the ethical considerations you would now take into account before getting direct-to-consumer genetic testing done? Provide two considerations. 1.   2.

When sending your saliva in to a direct-to-consumer genetic testing company they will perform to look for genetic variants, which requires prior identification of variants of interest and is for companies because it only looks at very specific places in the DNA. The genetic health risk report will determine your which is the increased likelihood of developing a particular disease based on your genetic makeup. Having an increased genetic risk for a disease means that you will  be affected by that disease in your lifetime. The  will use DNA sequence polymorphisms whose allele frequencies are significantly different in populations from different geographical regions of the world to determine your ancestry. 

Mutation B: Instead of the mutation in Question 25 a nucleotide (A)  is inserted after nucleotide 10, what is the mutant amino acid sequence?  

The recent announcement of the CRISPR-gene edited babies has prompted many prominent scientists and bioethicists to propose strict new guidelines that restrict human germline editing to be restricted to serious genetic diseases, and recommends couples should first attempt IVF with pre-implantation genetic diagnosis. 

Which of the following is INCORRECT regarding CRISPR?