Many drugs, substances, chemicals, or compounds can produce alterations in neural activity, brain function, and behavior through the following mechanism(s).

Metabotropic receptor subtypes 1 and 5 are generally excitatory in which of the following receptor families? (NOT necessarily only 1 and 5)

Gaseous and lipid neurotransmitters such as nitric oxide (NO) and anandamide (ANA), respectively, are typically released from post-synaptic sites, travel retrogradely, and have actions on pre-synaptic sites.

Why is storage in vesicles important?

What is the main difference between D1 and D2 dopaminergic receptors?

Which of the following are true about both catecholamine and indolamine synthesis?

Looking at the above figure, please pick two routes of administration and explain in the principles of ADME why they show different concentrations over time after drug administration.

Extra credit (2 points): What is your favorite drug we discussed? Why? What does it do? (e.g. NMDA antagonist)

Increasing the amount of GABA realeased would be able to overcome/prevent the effects of

Serotonin, dopamine, and norepinephrine