A 5-year-old girl is brought to the clinic by her parents, w…

A 5-year-old girl is brought to the clinic by her parents, who report that she has had poor appetite, weight loss, and a bloated abdomen over the past few weeks. They also noticed that she has started limping. On physical examination, she appears pale and quiet; small bruises on her shins and upper arms, hepatomegaly and splenomegaly. No heart or lung abnormalities. Which hematologic malignancy is the most likely diagnosis?

A 4-year-old child is brought to the emergency department wi…

A 4-year-old child is brought to the emergency department with rapid-onset fever, difficulty breathing, and a muffled voice. The parents report that the child refuses to lie down and is drooling excessively. On examination, the child appears anxious, sitting in a tripod position, and has inspiratory stridor. Acute epiglottitis is suspected. Which of the following are common signs and symptoms of acute epiglottitis in children? (Select all that apply)

A 6-year-old boy is brought to the pediatric clinic by his m…

A 6-year-old boy is brought to the pediatric clinic by his mother due to recurrent episodes of coughing, wheezing, and shortness of breath, especially at night and after playing outside. The provider explains to the mother that her child likely has asthma. Which of the following best describes childhood asthma?

A 2-year-old child presents to the clinic with chronic cough…

A 2-year-old child presents to the clinic with chronic cough, recurrent respiratory infections, and failure to thrive despite an adequate diet. A sweat chloride test is performed and confirms a diagnosis of cystic fibrosis (CF). Which of the following statements is accurate regarding the pathophysiology of Cystic Fibrosis?

A 25-year-old man presents to the clinic with a painless lum…

A 25-year-old man presents to the clinic with a painless lump in his neck that he first noticed three months ago. He reports occasional night sweats and unintentional weight loss of 10 pounds over the past few months. He denies fever, recent infections, or tenderness in the lump. A lymph node biopsy is performed and reveals a malignant proliferation of lymphoid cells. Which of the following is the most common site where Hodgkin lymphomas typically arise?

A 58-year-old man presents to the emergency department after…

A 58-year-old man presents to the emergency department after spending several hours gardening and mowing the lawn in hot weather. He reports experiencing muscle cramps, dizziness, and excessive sweating before arrival. He has no significant past medical history and is generally in good health. On examination, his skin is warm and flushed, his heart rate is elevated, and he appears mildly confused. Laboratory tests reveal: serum osmolality: Elevated and serum sodium: Borderline high. What is the likely explanation for this finding?