You’ve recently carried out an extensive extraction process…

You’ve recently carried out an extensive extraction process (fractionation) to isolate a new natural product from the leaves of the rare Sailfishius palmbeachifloridus found on the PBAU campus. The activity table for your experiment is shown here:  pH2 solvent pH2 aqueous pH9 solvent pH 9 aqueous + – + – Based on this information, answer the following questions: *** a) since the compound is not found in aqueous layers, the compound is:   *** b) the UN-IONIZED form(s) of the compound are found in which layer(s)? *** c) the unknown compound can be classified as:   *** d) You want to make sure your assay is working, so you repeat the same experiment using a laboratory standard shown below. Complete the table below (e.g. enter symbols, “+” or “-“) to predict what layer(s) the standard is likely to be found in using the same extraction process. pH2 solvent pH2 aqueous pH9 solvent pH 9 aqueous  

Recalling the term “ADME” … When a drug is administered to…

Recalling the term “ADME” … When a drug is administered to a patient, the concentration of the drug in the blood increases, and then falls with time. Question: Which of the four terms (A, D, M, or E) would most likely cause an INCREASE in the concentration of the drug in a patient’s fatty tissue?