A 65 kg female patient is currently on assist control with…

 A 65 kg female patient is currently on assist control with the following information:   Mode       AC                      pH            7.35 Freq         10                        PaCO2     50 mm Hg VT           600 ml                 PaO2        45 mmHg FIO2        .50                       HCO3       29 mEq/L PEEP         5                        BE            +3   What must be manipulated at this time?