A 69-year-old woman presents with fatigue and exertional dys…

A 69-year-old woman presents with fatigue and exertional dyspnea.  Her symptoms started 5 months ago and have progressively worsened.  Physical examination reveals a crescendo-decrescendo systolic murmur over the second left intercostal space. Echocardiogram demonstrates a thickened, relatively immobile valve.  14. Which of the following diagnoses is most consistent with the reported symptoms and signs?