Where do professional letters state the date?
Why is considering the purpose of a technical document impor…
Why is considering the purpose of a technical document important?
Where do professional letters state the writer’s contact det…
Where do professional letters state the writer’s contact details?
Technical documents use design to
Technical documents use design to
Find the average value of the function f(x) on the interval…
Find the average value of the function f(x) on the interval if
Shown below is the structure of the amino acid, tyrosine. P…
Shown below is the structure of the amino acid, tyrosine. Part A) 5 points How many acid-base equilibria do I have to consider in tyrosine? Use the table below to find out. Part B) 25 points The pKa values of tyrosine are 2.2, 9.11 and 10.07. Indicate what equilibria these pKa represent. Indicate the correct overall charge of each species. Part C) 10 points Indicate quantitatively which equilibria can be neglected in your calculation of contributions to total tyrosine concentration. Part D) 20 points Calculate the equilibrium concentrations of all molecular species present in a tyrosine solution at pH 9.5 that you obtained by mixing NaOH and tyrosine to give a solution that is 0.1 M in total concentration of this amino acid, tyrosine. Please do not fill in anything in the box provided below but instead upload your written answer as per instructions.
Consider the peptide below, it is made up of 9 amino acids….
Consider the peptide below, it is made up of 9 amino acids. The second amino acid, phenylalanine, has no ionizable groups that can engage in protonation/deprotonation equilibria in the pH range 0-14.
The Lennard Jones Potential as a function of distance combin…
The Lennard Jones Potential as a function of distance combines attractive and repulsive terms which leads to a minimum energy at a distance ro between two gas molecules or two atoms in a molecule.
Many but not all gas molecules have 3 translational and 3 ro…
Many but not all gas molecules have 3 translational and 3 rotational degrees of freedom.
Ozempic is the brand-name for semaglutide (S), a glucagon-li…
Ozempic is the brand-name for semaglutide (S), a glucagon-like peptide 1 (GLP-1) receptor (R) agonist used to improve glycemic control in type 2 diabetes mellitus, treat obesity, and reduce the risk of major adverse cardiovascular events. The dissociation constant of semaglutide binding to GLP-1 receptor has been reported to be in the range of 1 to 10 nM. The estimated number of receptors per cell is 10,000, corresponding to an approximate concentration of 10-8 M. After daily oral administration of 7 and 14 mg the blood concentrations of semaglutide were found to be 6.7 nmol/L and 14.6 nmol/L, respectively. After answering the questions A-C below, please fill out the following table: Dissociation constant Association constant