Given the vo vs. S plots below for an enzyme in the presence…

Given the vo vs. S plots below for an enzyme in the presence or absence of a competitive inhibitor, Enter True or False for each of the following statements. CompetitiveInhibition.png ​Prompt ​Response ​The K M a p p of the inhibited enzyme is larger than the KM of the uninhibited enzyme because the KM of the inhibited enzyme has changed. ​ ​Addition of more inhibitor will not change the K M a p p of the inhibited enzyme. ​ ​The vo at saturating substrate concentration will be the same for the inhibited and uninhibited reaction. ​ ​Using one-half the concentration of inhibitor will increase the vo at saturating substrate concentration. ​

The hemoglobin variant Hb Nancy contains a substitution wher…

The hemoglobin variant Hb Nancy contains a substitution where the beta chain Tyr-β145 is substituted with an aspartate. The result is disruption of the position of the C-terminal His-β146 so that it cannot form salt bridges with Lys-α40 and Asp-β94 such that the T state cannot be stabilized even in the absence of oxygen. The oxygen saturation curve for Hb Nancy is shown below compared to normal Hb A at pH 7.2 and pH 7.4. Use the graph to determine the Hb that best is associated with each property. AxSA4.png ​Prompt ​Response ​Greater Bohr effect ​ ​Greater cooperativity with respect to O2 binding ​ ​Greater affinity for O2 ​ ​More R state at low pO2 ​

The imidazole side chain of the hemoglobin beta chain residu…

The imidazole side chain of the hemoglobin beta chain residue His-β146 has a pKa of 7.9 when in the T state (shown below). Determine how its ionization state will change and how it will affect its interaction with the Asp-β94 side chain as the pH shifts from 7.2 in the muscle to 7.4 in the lungs. Enter Increase, Not change, or Decrease. 1b86.png ​Prompt ​Response ​His-β146 imidazole ionization state will ​ ​His-β146 imidazole interaction with Asp-β94 side chain will ​

Imagine the peptide structure below is part of a β-strand. G…

Imagine the peptide structure below is part of a β-strand. Given the labeled atoms identify each as contributing to or not contributing to β-sheet structure through hydrogen bonding. backboneHbond.png ​Position ​Contributes (enter Yes or No) ​a. ​ ​b. ​​ ​c. ​ ​d. ​​ ​e. ​​ ​f. ​​ ​g. ​​ ​h. ​​

Two of the corners of open rectangular box ABCDEFGH are B =…

Two of the corners of open rectangular box ABCDEFGH are B = (15, 3, 7) and H = (10, 9, 12). You are tasked with programming a drone to move from B to the midpoint of AD in 2 minutes, and then from there to G in 3 minutes. Provide two sets of parametric equations (one for the first part and one for the second part) that would accomplish this, using t = 0 to represent when the drone is at B.  Note: Your equations should give the equations of G when t = 5.     Click ‘True’ when finished