You are on an emergency medicine (EM) rotation rotation and…

You are on an emergency medicine (EM) rotation rotation and you have an elderly patient that has come to you because they raised the temperature in their hot tub as high as it will go and, after a few minutes in the very warm water, felt faint, past out, and nearly drowned (note that while the elderly tend to migrate to warmer climates, they are constantly at risk of overheating; however, this hot tub fainting effect can happen in younger people as well). What happened here with respect to vasodilation, venous return and cardiac output which led to them having to visit the emergency room (ER)/emergency department (ED)?  

For the following, use your knowledge of the protein-ligand…

For the following, use your knowledge of the protein-ligand interaction and the renal threshold/transport maximum: Why is there glucose in the urine (glucosuria, AKA glycosuria) of untreated diabetes mellitus patients with respect to what we know about the renal handling of glucose?