A 2 month old patient presents with extreme lethargy, poor cognitive development, and an overall failure to thrive.  What organ would you suspect is affected? 

A differential on a patient has a lower than normal neutrophil count (neutropenia).  Bone marrow results indicate a low M:E ratio and a low BM cellularity on this patient.  What can you conclude from these findings? 

A patient is admitted with a hemoglobin of 6.2 g/dl.  Patient is transfused 4 units of type specific packed red blood cells.  After patient history and demographics is determined, the physician wants a sickle solubility and hemoglobin electrophoresis performed on this patient.  What effect will the recent transfusion have on the patient results? 

Spectrin is an example of what type of protein and a defect in it is seen in which condition?

Match the error to the expected outcome.  What effect will the following have on the outcome of the sickle solubility test result? 

Which is a typical finding in paroxysmal nocturnal hemoglobinuria?

A patient who has blood type AB and is given blood type A would have which of the following: 

Diepoxybutane causes chromosomal breakage in which disorders?

A couple has recently come back from honeymooning in Costa Rica.  They are feeling under the weather, but attributed it to the change in climate.  The husband has now developed a fever that seems to spike in the morning and evenings after dinner.  During his fever episodes, he is suffering from chills and generalized aches all over his body.  Which of the following tests would best confirm this picture?

A patient’s labs show an increased LDH, a decreased haptoglobin, with moderate schistocytes and polychromasia on the peripheral blood smear.  The patient is suffering from: