MHC undergoes which of the following genetic rearrangements to create diversity in the binding site?

Centrocytes are found in the dark zone of germinal centers and centroblasts in the light zone of germinal centers.

The TCR gene segments (VDJ) use somatic recombination to create a functional gene that codes for the variable domain of TCR’s in T cells and variable domain of BCR’s in B cells.

What cells would be able to express an MHC presenting a peptide that is 8-10 amino acids in length?

Unproductive rearrangement on one chromosome (first attempt) of the B-cell receptor genes leads to:

You would expect the Igα and Igβ genes to be turned on (expressed) during which stage/s?

The proto-oncogene _____ is associated with the development of Burkitt’s lymphoma.

(Pesato) You are in the middle of writing a health certificate for a client when you notice one of the ewes limping. The client says “oh, it’s only foot rot”. You puff out your chest and get ready to lecture them on the difference between “foot rot” and “foot scald”. What is the most important thing you need to convey to this client?

(Grissett) Which of the following is a predisposing factor for development of abomasal impaction?

(Grissett) You are presented with a 4 year old Hereford cow with a 2 week history of lameness. The owner describes her as a grade 4 lameness. You look at the cow in a pen and note significant swelling of the limb with a draining tract pictured below. The owner informs you the cow is 6 months bred and cannot spend much money on treatment. What is your diagnosis and what is your treatment recommendation based on the owner’s financial constraint?