Zenalpha, a combination of medetomidine and a peripherally a…

Zenalpha, a combination of medetomidine and a peripherally acting selective alpha-2 antagonist vatinoxan, can be used as a premedication prior to isoflurane anesthesia.  When compared to the use of dexmedetomidine alone which premed will result in more hypotension while under isoflurane anesthesia?