Centroblasts are found in the dark zone of germinal centers and centrocytes in the light zone of germinal centers.

TCR diversity is established as a result of:

Receptor editing involves successive rearrangement at the light-chain loci when reactivity to cell surface repetitive self-antigens occurs during B-cell development.

What chemokine specifically attracts B cells to the primary follicle?

Imagine you are a doctor and you discover your infant patient has a missense mutation of the RAG proteins which leads to partial enzymatic activity of RAG enzymes which leads to symptoms that show as autoimmunity.  Based on what we have discussed in class, you conclude that:

What are possible consequences of non-productive rearrangement of the heavy chain?

MHC Class I presents ____ antigens to ____ T-cells.

A specific T-cell receptor will only recognize a peptide presented by a specific MHC molecule but will not recognize a different peptide presented by the same MHC molecule or the same peptide presented by a different MHC molecule. The T-cell recognition of antigen is said to be:

Which of the following is true about the pre-B cell receptor?

Imagine you are a doctor and you discover your infant patient has a missense mutation of the RAG proteins which leads to partial enzymatic activity of RAG enzymes which leads to symptoms that show as autoimmunity.  Based on what we have discussed in class, you conclude that: