A peptide 8 to 10 amino acids in length coming from an intracellular pathogen will be bound and presented by:

TCR molecules and BCR’s both have (complimentary determining regions) CDR’s/HV’s (hypervariable regions).

Which population of T cells has the highest relative abundance in the body?

In which stage of B-cell development do the Ig genes for the light chain begin rearrangement?

Which disease state is caused by loss of approximately 80 % of the RAG proteins enzymatic activity due to a missense mutation? (hint: infant has a red rash on the face and shoulders)

Which components listed below are part of signaling for a TCR?

Which population of T cells has the highest relative abundance in the body?

Matching (answers may be used more than once or not at all)

Which of the following component/s would be part of the CD3 complex?

Somatic recombination of T cells takes place in which of the following organs?