During a donor interview for apheresis platelet donation, th…

During a donor interview for apheresis platelet donation, the donor informs the interviewer that they have been taking aspirin daily for the past two years until discontinuing the medication one week ago.  What is the most appropriate course of action to take at the present time?

A 62-year-old female arrives at the hospital for cardiac sur…

A 62-year-old female arrives at the hospital for cardiac surgery. Pre-surgical laboratory testing is performed upon arrival.  The results are as follows: Hemoglobin/Hematocrit: 10.5g/dL/ 32% Platelet count: 45,000/uL Type & Screen: B D-Positive with Negative antibody screen Crossmatch (XM): 2 out of 2 units of RBCs compatible Priot to surgery, a platelet transfusion is ordered.  One B D-positive apheresis platelets (SDP) was issued and transfusion was begun after appropriate checks were completed.  Twenty minutes later, the pre-operative clinic calls the blood bank to report that the patient was experiencing the following symptoms after receiving just 20mL of the platelets: urticaria, pruritis, dyspnea, hypotension, and angioedema of the tongue, throat, and eyes.  The patient required immediate intubation to maintain her airway. Which of the following is the most likely type of transfusion reaction this patient was experiencing?

A 65-yr. old male who has multiple myeloma is currently rece…

A 65-yr. old male who has multiple myeloma is currently receiving monoclonal anti-CD38 immunotherapy (Daratumumab).                                                      Which of the following is used to treat reagent red cells in an effort to prevent interference of this drug with testing in the blood bank?