A 22-year-old woman presents with primary amenorrhea and cyc…

A 22-year-old woman presents with primary amenorrhea and cyclic pelvic pain. Physical exam reveals a shortened vagina and no visible cervix. Imaging confirms a hypoplastic uterus and obstructed vaginal canal. On further history, the patient reports that her mother took a nonsteroidal estrogen during early pregnancy. Which of the following medications is most likely responsible for this patient’s congenital anomaly?

A 45-year-old man presents with vertical diplopia that worse…

A 45-year-old man presents with vertical diplopia that worsens when going downstairs. On examination, the right eye is elevated in adduction, and he tilts his head to the left to compensate. Which cranial nerve is most likely affected, and what are its name, number, function, and exit foramen?

A 6-month-old infant presents with an abnormally elongated a…

A 6-month-old infant presents with an abnormally elongated and narrow skull. On exam, the anterior fontanelle is closed, and there is a palpable ridge along the midline of the skull. CT confirms early fusion of a midline calvarial suture. Which suture is prematurely fused, and which bones are involved?

A 5-year-old boy presents with colicky abdominal pain, bilio…

A 5-year-old boy presents with colicky abdominal pain, bilious vomiting, and distension. Abdominal X-ray reveals air-fluid levels consistent with small bowel obstruction. At surgery, a fibrous band is found connecting the ileum to the umbilicus, with a blind-ending pouch along the antimesenteric border. Which embryologic structure failed to involute?