Problem #1   The below structure has circular cross sections, is non-rotating, and made from 1020 cold rolled steel (Sy = 393MPa, Sut = 469MPa). It experiences a fully reversed torsion and a repeated axial force. The torsion varies from -150Nm and +150Nm. The axial force varies from 0 and 12kN.D = 30 mm, d = 25 mm, r = 1.5 mm. The notch sensitivity for the torsional load is qt = 0.82 and the notch sensitivity for the axial load is qa = 0.80.The material is room temperature and made with a reliability of 99%. The kc fatigue strength correction factor should be taken as 0.7. The item is polished so ka should be taken as 1.Do a fatigue failure analysis considering the point of analysis labeled in the figure.  The analysis should consider strength at infinite life.All static stress concentration factors should be found to the closest 0.05 from the graphs provided in Appendix C of your textbook.All dynamic stress concentration factors should be found to 3 significant figures from the provided equations as a function of the given notch sensitivity.After accounting for stress concentration factors, what is the magnitude of the alternating component of the stress in the x direction in units of MPa?MPa After accounting for stress concentration factors, what is the magnitude of the alternating component of the stress in the z direction in units of MPa?MPa After accounting for stress concentration factors, what is the magnitude of the mean component of the stress in the x direction in units of MPa?MPaAfter accounting for stress concentration factors, what is the magnitude of the mean component of the stress in the z direction in units of MPa?MPaWhat is the distortion energy result for the alternating components at the point of analysis in units of MPa?MPaWhat is the distortion energy result for the mean components at the point of analysis in units of MPa?MPaGiven that ka = kd = 1; ke = 0.814; kc = 0.7 please find the corrected fatigue strength in units of MPa. Please note that kb cannot be assumed to be 1 and should be found for the non-rotating structure.MPaWhat is the factor of safety for infinite life?

The PMHNP is considering using brexpiprazole for a patient with dementia experiencing severe agitation and psychosis. What is the most appropriate consideration for its use, given its pharmacological profile and the American Psychiatric Association’s guideline?

Match the drug type with the correct organism. Each one is worth a point.

Compare and contrast inactivated vs live attenuated vaccines.

Penicillin is a class of drugs that targets which specific portion of the bacterial outer membrane?

Which of the following is a narrow-spectrum antibiotic?

Which of the following drugs inhibits protein synthesis in bacteria?

Who and how were antibiotics discovered?

Why don’t sulfa drugs target mammalian cells? (mentioned that I was allergic sulfa drugs a couple of times so I want to see if you picked up on the context clue) 

In the figure, gray figures represent non-immune individuals; black figures represent immune individuals. Which population will be least likely to experience disease outbreak i.e. experience full signs and symptoms and all phases of the disease ?