What is/are the mechanism/s for bleeding in patients with severe liver disease?

Which of the following are components of the contact factor group of factors?

What tests are best to distinguish thrombotic thrombocytopenic purpura from DIC when a patient has schistocytes?

What is the role of thrombin-thrombomodulin complex?

The Treaty of  ended the Battle of Horseshoe Bend and forced the Upper Creeks to cede over 20 million acres of what is today Alabama to the US government.

The British Canadian territory north of Fort Detroit was known as “Lower Canada.”

In the INDIRECT pathway, glutamate release from motor cortex neurons in the striatum, ultimately neurons whose cell bodies are in the thalamus to movement. In the indirect pathway, the release of dopamine from the substantia nigra (SNc) neurons in striatum that express the D2 receptor. This dopamine release makes neurons in the thalamus to fire an action potential. Thus, in the indirect pathway the release of dopamine from the substantia nigra  movement.

The figure below is the same figure as in the previous question.     Which bar denotes the behavior of a “diseased” mouse after receiving a transplant of dopamine cells that expressed Halorhodopsin and whose brain is being illuminated by 543 nm light?

In class we discussed the paper, “Optogenetics enables functional analysis of human embryonic stem cell-derived grafts in a Parkinson’s disease model”. The figures below come from that paper. (FYI: Halorhodopsin-EYFP is the same thing as eNpHR3.0-EYFP)   Match each panel (A, B, and C) with the mouse genotype that could be responsible for the data. 

Loss-of-function mutations in the SCN2A gene will most likely cause autism/intellectual disability. 1) 1) This type of mutation will most likely neuronal excitability. 2) If an individual with this type of mutation develops seizures, does it make sense to treat them with a sodium channel blocker?