Chronic myelogenous leukemia is correlated with the presence…

Chronic myelogenous leukemia is correlated with the presence of the Philadelphia chromosome in lymphocyes.  The Philadelphia chromosome is the result of reciprocal translocation between chromosome 9 and chromosome 22.  Which of the following statements correctly describes the role of the Philadelphia chromosome in cancer?

Individuals who are genetically predisposed to developing ca…

Individuals who are genetically predisposed to developing cancer are often (            ) for one of tumor suppressor genes.  Cancer development is seen in cells in which the remaining normal allele is inactivated by a (                   ) mutation.  By pedigree analysis, inherited forms of cancer display a (                              ) inheritance pattern.