A 21-year-old woman presents with a primary complaint of men…

A 21-year-old woman presents with a primary complaint of menorrhagia (heavy menstrual flow). Her coagulation screen gives the following results. What disorder is most likely?    TEST RESULT REFERENCE RANGE PT 12.0 sec 11-13 sec APTT 40 sec 22-32 sec Factor VIII 35% 50-150% Platelet count 225,000/ul 150,000-450,000/ul RIPA 34% 50-150%

A patient is admitted to the local hospital due to abdominal…

A patient is admitted to the local hospital due to abdominal distention (swelling).  Upon physical examination, the physician notices a yellow ring around his eyes.  He has been suffering from swollen joints for the last month.  The physician in charge of his care runs a battery of labs.  The results are below: TEST Patient result Reference Range Prothrombin Time 16.8 sec 11-13 sec INR 3.85 NA Activated Partial Thromboplastin Time 71 sec 23-32 sec Bleeding Time 8 min 2-6 min Fibrinogen 375 mg/dl 200-400 mg/dl Factor X 22% >50% activity Factor II 21% >50% activity Factor VII 23% >50% activity Factor V 28% >50% activity Factor XII 95% >50% activity Factor VIII 98% >50% activity Factor XI 99% >50% activity Factor IX 30% >50% activity RIPA 95% >50% activity AST Elevated Normal ALT Elevated Normal GGT Elevated Normal TBIL Elevated Normal DBIL Elevated Normal Based on these findings, what is the most probable diagnosis?