A 42-year-old woman presents with generalized anxiety disorder (GAD). She describes persistent worry, muscle tension, and difficulty concentrating for several months. She has a history of alcohol use disorder but has been sober for two years. She is seeking a medication that can be used long term but is worried about dependence and sedation, since she works as an accountant and needs to stay alert. Which pharmacologic option is most appropriate? 

A 10-year-old boy with ADHD has been treated with amphetamine-dextroamphetamine XR 20 mg daily for the past month. His parents report that while his attention has improved, he has become increasingly irritable, anxious, and emotionally labile, especially in the afternoons. His appetite and sleep are otherwise stable. Physical exam is unremarkable, vitals are normal, and growth parameters are appropriate. What is the most appropriate next step in management? 

Which drug is most associated with first-dose syncope? 

A 58-year-old man with a long history of alcohol use disorder is brought to the ED by his family for confusion, unsteady gait, and abnormal eye movements. On exam, he is disoriented to time, demonstrates a wide-based ataxic gait, and has bilateral lateral rectus palsy. Vitals are stable. Labs show mild macrocytic anemia and elevated AST > ALT. The NP suspects Wernicke’s encephalopathy. Which is the most appropriate immediate intervention? 

Which counseling point is essential for nitroglycerin therapy? 

Which opioid adverse effect does not develop tolerance? 

Sodium depletion has which effect on lithium therapy? 

A 62-year-old man with HTN is prescribed amlodipine. Which adverse effect should the NP anticipate? 

Physical dependence occurs when: 

Which element is legally required on a prescription?