Stem: A 66-year-old man with a history of coronary artery di…

Stem: A 66-year-old man with a history of coronary artery disease develops chest pain during exertion. Laboratory tests reveal elevated troponin levels. His condition is attributed to myocardial ischemia. Which of the following is the earliest and most critical consequence of cellular hypoxia in this scenario?

A 25-year-old female comes to you with a 4-months history of…

A 25-year-old female comes to you with a 4-months history of fatigue. Her history is unremarkable; she had no major medical illness. She has noticed that during the past 12 months her menstrual periods have become heavier and longer for 7 to 9 days with very heavy flow. On examination, the patient appear pale , BP 100/70 mmHg. Blood smear is shown below. Her Hb is 9.5 g/dl. What is the most likely cause of her disease?