BCH4024 OC F25 E3 Q44: The amino acid aspartate is synthesized from ________ by a transamination reaction involving ________.

BCH4024 OC F25 E3 Q41: A 14-month-old child is brought to the clinic with swelling in the legs, irritability, and flaky skin lesions. The child was recently weaned and is now fed a maize-based porridge, which provides adequate caloric intake but is low in protein. Physical exam reveals a distended abdomen and sparse, depigmented hair. What is the most likely diagnosis?

For questions 42 & 43, choose from the nucleotides whose structures are shown below. Each nucleotide can be used more than once or not at all in these questions. You might find it helpful if you identify each compound by its name before attempting to answer the questions. BCH4024 OC F25 E3 Q42: Which of the above nucleotides (A–E) is an intermediate in de novo pyrimidine synthesis and is converted to UMP?

BCH4024 OC F25 E3 Q19: A 12-year-old female who presented with severe abdominal pain was found to have a plasma triglyceride concentration of 750 mg/dL (normal:

BCH4024 OC F25 E3 Q24: A 45-year-old man has elevated LDL cholesterol and a family history of early-onset coronary artery disease. Genetic testing reveals a mutation in the LDL receptor gene. Which apolipoprotein is required for LDL receptor binding?

BCH4024 OC F25 E3 Q9: Which of the following is the direct precursor to CTP in pyrimidine biosynthesis?

BCH4024 OC F25 E3 Q11: A healthy boy was born uneventfully to apparently normal parents. Delayed acquisition of motor skills was suspected by 3 months of age. At 12 months of age, involuntary twisting and stiffening movements emerged. At 3 years of age, he began to chew on the inside of his lip and occasionally on his index finger. Elevated levels of uric acid were also found in a blood test. The child diagnosis is ______________________ and results from a deficiency in the activity of ________________?

Questions 32 & 33 deal with the following case: A 16-year-old boy with known type 1 diabetes presents with vomiting, abdominal pain, and rapid breathing. He missed his insulin doses for two days. Labs show: Blood glucose: 520 mg/dL Serum ketones: high Arterial pH: 7.10 Bicarbonate: low Plasma free fatty acids: elevated Urine glucose and ketones: positive BCH4024 OC F25 E3 Q33: What is the biochemical basis of the acidosis?

BCH4024 OC F25 E3 Q5: Starting with free ammonium ions and the carbamoyl phosphate synthetase reaction, which of the following is CORRECT?

For questions 34 through 36, choose from the nucleotides whose structures are shown below. Each nucleotide can be used more than once or not at all in these questions. You might find it helpful if you identify each compound by its name before attempting to answer the questions. BCH4024 OC F25 E3 Q35: Which of the above nucleotides (A–E) is an allosteric activator of AMP-activated protein kinase (AMPK)?