Match the following drugs with the relevant adverse effects. Each drug may be used more than once or not at all:
A child is admitted to the pediatric unit with increased sec…
A child is admitted to the pediatric unit with increased secretions, cough, and nasal drainage. Physician diagnoses the child with RSV. A priority nursing diagnosis would be:
A newborn is being discharged to home. The nurse is setting…
A newborn is being discharged to home. The nurse is setting up a referral to see a Pulmonology specialist to rule out Cystic Fibrosis (CF). What is the earliest recognizable clinical manifestation of CF?
You are working with a family with and a child who has a con…
You are working with a family with and a child who has a congenital heart defect. Future surgery is planned and you are teaching the parent how to reduce cardiac demands. The parent needs more teaching when she says which of the following?
A relatively small number of genes appear to account for muc…
A relatively small number of genes appear to account for much of the variation in skin color observed in humans. Two genes that have undergone positive selection in northern latitudes are OCA2 in Asian populations and SLC24A5 in European populations. In the ancestral African population, the SLC24A5 gene produces a protein with an alanine at amino acid position 111. In the European population the amino acid at position 111 is threonine. The protein that is produced from the SLC24A5 gene exchanges an ion of Na+ from the cell cytoplasm for a Ca2+ ion on the outside of the cell. This exchange appears to be necessary for normal melanin synthesis. In East Asian populations, the OCA2 gene produces a protein with the amino acid arginine at position 618 whereas the ancestral amino acid at that position is histidine. For both genes, the mutation arises from a single base change called a Single Nucleotide Polymorphism The mutations in the SLC24A5 gene affects protein expression in ___________________ while the pigments produced and secreted from these cells are taken up by __________________.
Binding of a hormone to the receptor depicted in the accompa…
Binding of a hormone to the receptor depicted in the accompanying figure would cause the receptor to bind __________ near its carboxy terminus.
Covalent bonds are formed between amino and carboxy groups i…
Covalent bonds are formed between amino and carboxy groups in proteins by:
The mushroom Amanita phalloides contains a peptide called al…
The mushroom Amanita phalloides contains a peptide called alpha-amanitin. This toxin blocks Pol II which catalyzes phosphodiester bond formation between ribose sugars in mRNA. The initial effect of the toxin is to block:
Epidermolysis bullosa is an inherited disease where keratino…
Epidermolysis bullosa is an inherited disease where keratinocytes separate from the dermis. You would expect that the mutations which cause this disease to be genes that encode for proteins found in:
Hydrogen bonding between the carbonyl oxygen of one amino ac…
Hydrogen bonding between the carbonyl oxygen of one amino acid and the hydrogen on the amine of a nearby amino acid in an i + 4 arrangement is responsible for the _______ structure in proteins.