Patients with familial hypercholesterolemia have __________.

Which of the following is targeted by the mycolactone virulence factor secreted by the pathogenic bacterium Mycobacterium ulcerans?

Mutations in ______________ have been linked to an hereditary form of gastric cancer.

Which of the following is essential for formation of multivesicular bodies?

PICALM __________.

What is the influence of each interfacial tension (e.g. liquid, solid, etc; high or low) on contact angles?

 A 45-year-old woman has a history of type 2 diabetes. She is currently managed with metformin 1g TDS and pioglitazone 30mg OD. She has attended her annual diabetic review and her HbA1c is recorded.   Which of the following is the MOST appropriate target HbA1c result for this patient?

Section B Short Answer Questions. Please attempt all questions.

Draw a schematic of water droplet on a surface and label all the interfacial tensions.  Write the Young’s equation and explain each term and its significance.  You can type in the equation OR write this on a piece of paper along with sketch and then take a picture with your cell phone.  You can submit this separately in “Exam 1 Submission” that is listed in Assignments tab under Exam 1.

 The following question relates to an emergency supply at the request of a prescriber.   Which of the following statements is INCORRECT?