A 58-year-old patient was taken to surgery for debridement o…

A 58-year-old patient was taken to surgery for debridement of the left sinus. Direct smear of the clinical material from the left sinus obtained at the time of surgery indicated the presence of a mucormycete (zygomycete). Which of the following factor(s) predisposes an individual to infection caused by the group of fungi? Select all that apply.