An irritation to the skin from a chaffing shirt label is a _…

An irritation to the skin from a chaffing shirt label is a ___________ detected by a ___________. This information is sent to a _______________, the brain, where it is determined that the skin irritation is out of normal range. The brain sends signals to _____________ that cause physiological responses to return the variable to normal homeostatic range.  Obj 1.6/ 1.7