A 60-year-old patient presents with knee pain and stiffness,…

A 60-year-old patient presents with knee pain and stiffness, especially in the morning, which reportedly improves after 30 minutes. X-rays show joint space narrowing and osteophytes ; a diagnosis of osteoarthritis (OA) is made. What should the APRN advise as best first-line pharmacologic treatment for this patient?