Here is a set of homologous sequences from three different primates for a gene responsible for the higher intelligence observed in primates. We are interested in understanding where transcription factors bind upstream of the gene so that we can attempt to modulate the expression of the gene in individuals with decreased cognition in a highly experimental treatment (i.e., this would never work in reality). We discussed several different approaches for finding motifs in sequences. The sequences are reprinted for each question that requires you to use the sequences. GTTCAG AATCAG TATTCG Use a GreedyMotif search to find motifs for these sequences. Assume you are looking for 4-mers and work your algorithms so there’s never a 4-mer with zero probability in your matrix. If there is a random component, make sure you clearly tell me what the “random” choice is and make sure that it is evident to me that you understand what random means in the context of the greedy motif search (i.e., if there is a random component, explain it to me in words and demonstrate its appropriate use). Make sure you report the score for each set of motifs. If you don’t provide sufficient detail for me to see that you understand what to do, your writing is too messy to read, or the different steps are scattered across the page, giving you credit will be challenging. 

A patient recovering from a lumbar puncture rates a headache as being 8 on a pain scale of 0 to 10. What action by the nurse is indicated?

The nurse is completing a Mini Mental Status Examination with a patient. What should the nurse ask to evaluate immediate memory?

Which technique should the nurse use to assess a patient’s facial nerve (CN VII)?

During a neurological assessment the nurse asks a patient to close her eyes and identify a letter drawn on the patient’s palm. What is the nurse assessing?

Ordered: 1000 mL Lactated Ringer’s IV over 3 hours Available: Macrodrip set, 15 gtts/mL Calculate the gravity flow rate without the use of an infusion pump. Round to the whole drop ___________________gtt/min

Ordered: Heparin Sodium 1250 units/hour Available: 20,000 units in 250mL’s of D5W At what rate will you set the IV pump to deliver this dosage? Round to the tenth __________________mL/hr

Order: Dobutamine 5 mcg/kg/min Available: Standard solution of 1 gram in 250 mL D5W Patients weight:  440 lbs. What will you set the infusion pump at to deliver the ordered dose? Round to the tenth ________________________mL/hr

The order is written to give IV Vancomycin 500 mg. q 6 hrs. for endocarditis, slow infusion over 90 minutes.  Your pharmacy provides a Vancomycin solution strength of 750mg/150mL. At what rate will you set the IV pump to deliver the ordered dose? Round to the tenth ______________mL/hr

Ordered: levothyroxine sodium 175 mcg. IV Available: levothyroxine sodium powder for IV injection 0.2 mg./vial When reconstituted, vial contains 6 mL. How much will you draw up to give? Round to the tenth _____________mL