The hemoglobin variant Hb Nancy contains a substitution where the beta chain Tyr-β145 is substituted with an aspartate. The result is disruption of the position of the C-terminal His-β146 so that it cannot form salt bridges with Lys-α40 and Asp-β94 such that the T state cannot be stabilized even in the absence of oxygen. The oxygen saturation curve for Hb Nancy is shown below compared to normal Hb A at pH 7.2 and pH 7.4. Use the graph to determine the Hb that best is associated with each property. AxSA4.png ​Prompt ​Response ​Greater Bohr effect ​ ​Greater cooperativity with respect to O2 binding ​ ​Greater affinity for O2 ​ ​More R state at low pO2 ​

Determine the stereochemistry of each amino acid in the dipeptide below. Enter D or L. Ax3aSA_peptideStructure.png ​Residue position ​Stereochemistry ​N-terminal amino acid ​ ​C-terminal amino acid ​

Imagine the peptide structure below is part of a β-strand. Given the labeled atoms identify each as contributing to or not contributing to β-sheet structure through hydrogen bonding. backboneHbond.png ​Position ​Contributes (enter Yes or No) ​a. ​ ​b. ​​ ​c. ​ ​d. ​​ ​e. ​​ ​f. ​​ ​g. ​​ ​h. ​​

Two of the corners of open rectangular box ABCDEFGH are B = (15, 3, 7) and H = (10, 9, 12). You are tasked with programming a drone to move from B to the midpoint of AD in 2 minutes, and then from there to G in 3 minutes. Provide two sets of parametric equations (one for the first part and one for the second part) that would accomplish this, using t = 0 to represent when the drone is at B.  Note: Your equations should give the equations of G when t = 5.     Click ‘True’ when finished

Without using dot products, determine whether the angle XYZ is a right angle, if X = (3, -5, 4); Y = (-2, -2, -2) and Z = (1, 5, -1)     Click ‘True’ when finished

By adding one horizontal line to the diagram, find the value of x:     Click ‘True’ when finished

Find a vector of length 4 that is perpendicular to     Click ‘True’ when finished

You are Democritus

What is the difference between a physical and a chemical change? provide one example of each.

A substance that has only one component is a _______ substance. A substance that has multiple components is a _______ .