This anticoagulant agent acts in several sites of the coagulation cascade, with its principle action being inhibition of factor Xa and can be reversed with protamine. Which anticoagulant has this mechanism?

Sacubitril/valsartan has class I level of evidence justifying its use as an agent that is GDMT (Guideline directed medical therapy.) What mechanism of action provides its effects?

A 26 yo male in your care has been diagnosed with major depression syndrome. You wish to start him on pharmacologic therapy, but he expresses significant concern regarding sexual side effects. Which of the following depression medications is an option that will reduce the risk of sexual dysfunction?

Over 2million children die each year of pneumonia, many in Sub-Saharan Africa. What health maintenance strategy for sickle cell disease prevents pneumonia in children less than five years of age if given compliantly?

PS is a 52 yo female status post total hysterectomy and double oophorectomy. She has no significant cardiovascular medical history, and her only medication is gemfibrozil (Lopid) 600mg bid for hypertriglyceridemia. She comes to the clinic with complaints of night sweats, hot flashes every 20 minutes, and vaginal irritation with sexual intercourse. Which is the BEST menopausal hormone therapy option?

Dabigatran is indicated in nonvalvular atrial fibrillation, venous thromboembolism, and VTE prophylaxis. If it needs to be reversed, the appropriate agent is:

A 55-year-old female with a history of chronic kidney disease presents with fatigue and pallor. Her hemoglobin is 9.0 g/dL, and her serum ferritin is 10 ng/mL. She weighs 60 kg. The patient is currently on a regimen of darbepoetin 500 mcg SC every three weeks. The decision is made to initiate parenteral iron therapy. Which of the following is the most appropriate treatment plan for this patient?

Samantha is a 30-year-old woman who has been diagnosed with bipolar 2 disorder. She has a history of hypomanic and depressive episodes, with symptoms that include increased energy, impulsivity, and feelings of sadness and hopelessness. Her psychiatrist recommends starting pharmacotherapy to stabilize her moods and prevent relapses. Based on current guidelines, which medication is FDA approved for treating bipolar 2 with depression disorder?

A 10-year-old African American boy with a known history of sickle cell disease presents to the emergency department with sudden abdominal pain and distension. His mother reports that he has been lethargic and pale for the past few hours. On examination, he is tachycardic, hypotensive, and has a markedly enlarged spleen. Laboratory tests reveal a significant drop in hemoglobin and platelet count. The patient is admitted for a splenectomy and stabilization of his sickle cell disease. Which of the following treatments will lower fetal HgbF, decrease mortality and morbidity, and decrease hospitalizations by 50%?

The nurse assigned to care for multiple clients is reviewing the laboratory reports. Based on the information provided, in which sequence should the nurse assess the clients? Prioritize the order in which the nurse should plan to assess the clients. The client with renal insufficiency whose serum potassium level is 5.2 mEq/L The client with hyperemesis whose serum sodium level is 122 mEq/L The client recovering following head trauma whose serum osmolality is 290 mOsm/kg The client with DM whose ABG results are pH = 7.22, PaCO2 = 35 mm Hg, HCO3 = 15 mEq/L