You are a molecular biologist studying how the membrane rece…

You are a molecular biologist studying how the membrane receptor FGFR1 influences heart development in chickens. You prepare a set of slides with sections of embryonic chicken heart cells for indirect immunoflourescence to examine the distribution of FGFR1 in these cells. Which combination of antibodies should you use for this experiment?

Membrane fusion between a vesicle and the plasma membrane is…

Membrane fusion between a vesicle and the plasma membrane is mediated by vSNARE/tSNARE binding. TRUE or FALSE:  This involves a stage in which a temporary lipid bilayer is formed between the original leaflet closest to the vesicle lumen and the original leaflet closest to the extracellular space (the area outside of the cell). 

A mouse line in Dr. Tolentino’s laboratory has acquired a no…

A mouse line in Dr. Tolentino’s laboratory has acquired a novel mutation impacting receptor-mediated endocytosis. When Dr. Tolentino examines the mouse cells under a microscope, she observes that coated pits and coated vesicles are forming, but they are accumulating at the plasma membrane and none are appearing in the cell cytosol, suggesting they they are not pinching off the cell surface.  What protein do you suspect the novel mutation has occurred in?