Miss C, a 23-year-old woman presents to her local sexual hea…

Miss C, a 23-year-old woman presents to her local sexual health clinic with unusual vaginal discharge and lower abdominal pain for the past week. She also reports increased urinary frequency and discomfort during urination. The symptoms started mildly but have progressively worsened. She reports no fever or chills.   Past Medical History Hypothyroidism (2023)   Drug History Mercilon (ethinylestradiol 20 micrograms, desogestrel 150 micrograms) Drug allergies – Ofloxacin (rash)   Social History Lives alone Full time professional employment Sexually active with a new partner for the past two months. They occasionally use condoms. Non-smoker Drinks alcohol 10-15 units per week   Observations and test results: BP: 128/72 mmHg Heart rate: 70 beats per minute Respiratory rate: 15 breaths per minute Temperature: 37.1 degrees C BMI: 20 kg/m2 Abdominal exam: Mild tenderness in the lower abdomen, no rebound tenderness Pelvic exam: Mucopurulent discharge, cervical motion tenderness FBC: normal Urinalysis: no signs of urinary tract infection NAAT: positive for Neisseria gonorrhoeae

Miss C asks about whether her levothyroxine tablets should b…

Miss C asks about whether her levothyroxine tablets should be continued while breastfeeding. What is the most appropriate action to take regarding levothyroxine treatment during breastfeeding? Drugs and Lactation Database (LactMed®) – NCBI Bookshelf (nih.gov)  

Three years later Mr A attends for his annual diabetic revie…

Three years later Mr A attends for his annual diabetic review.   Repeat medication Allopurinol 300mg tablets, take one daily Amlodipine 10mg tablets, take one daily Canagliflozin 300mg tablets, take one daily Losartan 100mg tablets, take one daily Metformin 500mg tablets, take two twice a day   Blood tests were requested which come back as follows Test Result Sodium 138                               (135 – 145mmol/L) Potassium 4.7                                (3.5 – 5.0mmol/L) Urea 6.2                                (2.5 – 6.7mmol/L) Creatinine 148                              (baseline 140) (70 – 150µmol/L) Haemoglobin 15.2                              (11.5 – 16.5g/dL) HbA1c 64                                 (90mL/ min)