The following combination of drugs is appropriate as a triple therapy regimen for eradication of Helicobacter pylori:                                                                                                     1.        Omeprazole + Amoxicillin + Clarithromycin2.        Esomeprazole + Amoxicillin + Cimetidine3.        Dicyclomine + Amoxicillin + Clarithromycin4.        Ranitidine + Metronidazole + Doxycycline5.        Metronidazole + Doxycycline + Clarithromycin

The following drug is classified as a H2-receptor antagonist:                                      1.        Loperamide2.        Infliximab3.        Metoclopramide4.        Pantoprazole5.        Ranitidine

The drug of choice for patient with an acute angina attack is:                                                                                                                                                    1.  Spironolactone2.  Verapamil 3.  Glyceryl trinitrate 4.  Ranolazine5.  Isosorbide mononitrate

The following drug interacts with phosphodiesterase inhibitors such as sildenafil and           tadalafil:                                                                                                                                                     1.  Acetylsalicylic acid     2.  Atenolol     3.  Tranexamic acid     4.  Glyceryl trinitrate     5.  Perindopril 

The following route of administration bypass the first pass metabolism except:       1.        Intravenous2.        Oral3.        Sublingual4.        Inhalation aerosol5.        Transdermal

 The following drug is a cholesterol absorption inhibitor:                                                1.  Atorvastatin2.  Nicotinic acid3.  Gemfibrozil4.  Cholestyramine5.  Ezetimibe

The following is true about distribution of lipophilic drugs:                                            1.        They do not dissolve in the lipid membranes.2.        They move across most biologic membranes.3.        Blood flow does not influence its distribution.4.        Lipophilic drugs with low molecular weight cannot move into the interstitium.5.        Lipophilic drugs with high molecular weight pass through the slit junctions of the capillaries.

 The following drug is a potassium sparing diuretic used in the treatment of heart           failure:                                                                                                                                        1.   Amlodipine     2.   Hydrochlorothiazide     3.   Enalapril     4.   Spironolactone     5.   Digoxin 

The following gastrointestinal agent is contraindicated in pregnancy:                         1.        Calcium carbonate2.        Famotidine3.        Lansoprazole4.        Misoprostol5.        Docusate

The following are factors which influence absorption of a drug except:                       1.        Extracellular fluid2.        Blood flow3.        Total surface area4.        Contact time5.        Effect of pH