A patient is experiencing pinpoint petechial bruising on her…

A patient is experiencing pinpoint petechial bruising on her upper torso. Her history revealed frequent nosebleeds during her childhood. Clot-based screening assays are within normal reference ranges, and platelet function assays are abnormal. Based on this information, what appears to be defective in this patient?

A 1 year old male is sent for a hematology consult due to ex…

A 1 year old male is sent for a hematology consult due to excessive bruising, epitaxis, and gingival bleeding. Platelet aggregation shows the following:   Wave 1: ADP.                   Wave 2: Collagen           Wave 3: Epinephrine.    Wave 4: Ristocetin What is this patient’s most likely disorder of primary hemostasis?

A 5 year old male is sent for a hematology consult due to ex…

A 5 year old male is sent for a hematology consult due to excessive nose bleeds. It is noted that he has a lot of gingival bleeding and bruises easily. Platelet aggregation shows the following: Wave 1: ADP.                   Wave 2: Collagen           Wave 3: Epinephrine.    Wave 4: Ristocetin The MLS ran one more aggregation study and found no response when the patient’s platelets were mixed with a combination of ristocetin and reagent-based vWF. What is this patient’s Disorder of primary hemostasis?