Spleen cells are taken from a mouse immunized with the LCM virus.  2 assays are used to determine antigen-specific functional activity of the spleen cells.   Assay 1: the spleen cells (T cells) are incubated with macrophages that have been briefly exposed to LCM virus (phagocytized the virus), production of IL-2 by the T cells is considered a positive response. Assay 2: the spleen cells are incubated with LCM-infected target cells, lysis of the infected target cells is considered a positive response. Activity of which cell population is detected in Assay 2?

Identify which of the following cells are myeloid and which are lymphod:

In antibody gene rearrangement, what is allelic exclusion?

Spleen cells are taken from a mouse immunized with the LCM virus.  2 assays are used to determine antigen-specific functional activity of the spleen cells.   Assay 1: the spleen cells (T cells) are incubated with macrophages that have been briefly exposed to LCM virus (phagocytized the virus), production of IL-2 by the T cells is considered a positive response. Assay 2: the spleen cells are incubated with LCM-infected target cells, lysis of the infected target cells is considered a positive response. The functional activity of which MHC molecules is detected in Assay 1?

What are high endotheilial venules (HEVs)?  Are they involved with lymphocyte or leukocyte extravasation?

List the primary lymphoid organs and summarize their functions in the immune system. (make sure you explain)

What is the difference between B-2 cells and B-1 cells?  Which group is TI and which is TD?

Identify this molecule (whole molecule):

What type of B cell leaves the bone marrow?

What is the purpose of a complete B-cell receptor, why is it not enough to just have membrane bound antibody on a B cell?