Suppose a team of researchers studied if American adults age…

Suppose a team of researchers studied if American adults aged 30-35 with post-traumatic stress disorder (PTSD) are at higher risk of alcohol use disorder. The researchers designed a prospective cohort study to study the association between PTSD and alcohol use disorder. In the first step the researcher included a random sample of American adults aged 30-35. Any individuals with alcohol use disorder at the start of the study were excluded from the study. In the second step, the researchers used medical records to determine if the participants had a diagnosis of PTSD. After five years of follow-up, the researchers interviewed the participants to determine if the participants had developed alcohol use disorder.   After hearing about this study, a fellow researcher is concerned that participants may not feel comfortable disclosing that they have alcohol use disorder. The fellow researcher warns their colleagues that this may bias the effect estimate from this study.   What source of bias is the fellow researcher concerned about?

Suppose a researcher conducted a cross-sectional study on at…

Suppose a researcher conducted a cross-sectional study on attention deficit hyperactivity disorder (ADHD) and externalizing behaviors (e.g., rule-breaking or defiant behavior) among adolescents in Hillsborough County. During the summer months, the researcher works as a volunteer at a summer education program for adolescents who struggle with their schoolwork. Since the participants of the summer education program are adolescents, the researcher decides to invite the adolescents who attend the summer program for participation in the study.   The researcher is worried that there might be selection bias in the estimate of the effect of ADHD on externalizing behaviors because ADHD and externalizing behaviors are both reasons for participation in the summer program and are therefore also both affect study participation. To assess potential selection bias, the researcher drew the directed acyclic graph (DAG) in Figure 2.   Based on the DAG in Figure 2, will there be selection bias (yes/no)? (2 points) Explain your answer (max. 4 points).

Case 1 (Questions 11-13) Suppose a team of researchers condu…

Case 1 (Questions 11-13) Suppose a team of researchers conducts a case-control study on the association between hypertension and stroke among adults aged 50 and older in Florida. For this study, the researchers selected Floridian adults aged 50 and older who experienced a stroke as the cases. As controls, the researchers selected Floridian adults aged 50 or older who did not experience a stroke. To assess each participant’s exposure status, the researchers asked the participants to fill out a questionnaire in which the participants were asked to retrospectively report if they have had hypertension in the past. What source of measurement error could affect the measurement of hypertension in case 1? (2 points) Explain why you chose this source of measurement error (2 points).