Evaluate the hematology data and identify the most likely diagnosis: WBC Count: 12.5 x 10⁹/L RBC Count: 4.6 x 10⁶/µL Hemoglobin (Hgb): 13.8 g/dL Hematocrit (Hct): 41% Platelet Count: 180 x 10⁹/L Differential Count: Neutrophils: 35% Lymphocytes: 50% Monocytes: 10% Eosinophils: 3% Basophils: 2%  

In hemoglobin C disease, how does the mutation affect the hemoglobin molecule?

A patient has the following CBC values WBC = 10.2 x 109/L RBC = 5.5 x 1012/L HGB = 11.3 g/dL HCT = 35.3 L/L MCH = 20 pg MCHC = 32.0 g/dL MCV = 64 fL PLTS = 222 x 109/L Using this data, calculate and interpret the mentzer index:    

In a 1 month old with alpha thalassemia, you would expect to find:

Evaluate the images of scatterplots from the Sysmex-XN. Match each diagnosis with the corresponding scatterplot image.  

A 62-year-old patient presents with complaints of fatigue, pallor, and occasional shortness of breath. On examination, he has pale conjunctiva and mild glossitis. A CBC reveals the following results: Hemoglobin: 8.5 g/dL  MCV: 115 fL WBC: 3.2 x 10⁹/L  Platelets: 95 x 10⁹/L  Reflex Tests Ordered: Serum Vitamin B12: Low Serum Folate: Normal Serum Iron: Normal Bone Marrow Biopsy: Hypercellular with dysplasia in all three cell lines. Based on the clinical findings and laboratory results, which is the most likely diagnosis, and what features differentiate this diagnosis?    

Evaluate the peripheral blood smear and selected cell images below. Based on these findings, rank the following tests by order of importance to evaluate the case:  

Based on observation of the image below, how would you classify this finding?  

A 7-year-old child presents with fatigue, pallor, and growth delay. The CBC and peripheral smear results are as follows: WBC Count: 25.0 x 10⁹/L RBC Count: 5.8 x 10⁶/µL Hemoglobin (Hgb): 6.5 g/dL Hematocrit (Hct): 19% MCV: 65 fL MCH: 18 pg MCHC: 30 g/dL RDW: 16.1% Platelet Count: 450 x 10⁹/L NRBCs: 35 per 100 WBCs Peripheral Smear Findings: Microcytic, hypochromic RBCs. Target cells, anisocytosis, poikilocytosis, and basophilic stippling. Numerous NRBCs. Based on the laboratory data and peripheral smear findings, what is the next best step in the workup of this sample?  

Maternal Recognition of Pregnancy Define maternal recognition of pregnancy. Provide the signal and mechanism for this process in humans, cows, mares, and dogs. Describe or diagram implantation of the human conceptus. Please include in your answer differentiation of trophoblastic cells, the steps with implantation, and classification of the placenta – both shape/contact point and layers of tissue between maternal and fetal blood.