Pretend you are a scientist who has just conducted a GWAS. Y…

Pretend you are a scientist who has just conducted a GWAS. Your GWAS shows SNP 1 in the image below as the lead SNP associated with a disease. (This would be the SNP with the tallest peak on your Manhattan plot.) SNP 1 is in a non-coding region of the genome, so it’s not clear how a SNP allele at this locus would increase risk for disease. Thus, you look for more information to make a hypothesis about which SNP locus might be the functional/causal SNP (i.e., the locus with a SNP allele that actually increases risk of developing the disease). You have the information below:   Based on the information above, the best hypothesis is that SNP is the functional SNP. (Keep in mind, you will need to do more experiments to provide evidence to support this hypothesis.) From the list provided, which SNP is in linkage equilibrium with SNP 1?

The following case will be used for Questions 5-9: Mr. Z is…

The following case will be used for Questions 5-9: Mr. Z is a 72-year-old nursing home resident who has fallen 4 times in the past month.  Mr. Z walks quickly with short steps, he slows to a complete stop when he turns corners, and he takes close to 5 minutes to sit up and get out of his bed.   Based on recent evidence, why would a therapist prescribe an aerobic program for Mr. Z.?

You MUST NOT use anything during this exam except a notes pa…

You MUST NOT use anything during this exam except a notes page as explained under IT366 Final Exam | Overview.Read the following statement: —- I am familiar with the requirements of the Mason Honor Code.I have complied with those requirements in all respects in relation to this exam.I hereby declare that the following work is entirely my own and has been completed in accordance with the directions of the Instructor and exam supervisor(s).—-Enter your full name  and your Mason G Number  to make the above declaration.(No points, but your exam will not be graded if you do not complete this question.)