A woman visits her physician with a complaint of polyuria and polydipsia. She has a family history of type 2 diabetes mellitus and is concerned that she is developing the disease. The physician notes that her previous hemoglobin A1c (Hb A1c) value was 6% (considered within healthy reference interval in the physician’s practice) with a fasting plasma glucose of 95 mg/dL. At this visit, her Hb A1c value is 8.5%. Why would the physician be correct to order an oral glucose tolerance test (OGTT) for this individual?

An example of a confirmatory laboratory test used to verify a borderline abnormal newborn screening test result in an asymptomatic individual would be gas chromatography combined with mass spectrometry, particularly for organic acid analysis.

According to the toxicology guest speaker, what is the first piece of information to inquire when interpreting a toxicology result?

All of the following factors must be demonstrated before metal toxicity is considered a diagnosis except:

List 3 factors that influence enzymatic reactions?

Severe hypothyroidism that develops during the newborn period is referred to as

A 6-year-old girl has complained about painful urination and is taken to her pediatrician. There is NO family history of CHD or any lipid abnormalities. After a fasting blood specimen and urine specimen are obtained, laboratory findings are as follows (healthy reference intervals are in parentheses): serum albumin 1.8 g/dL (3.5–5.5 g/dL), total serum cholesterol 215 mg/dL, LDL cholesterol 130 mg/dL, serum triglyceride 250 mg/dL, serum blood urea nitrogen (BUN) 23 mg/dL, heavy urine protein (normal is negative), and 1+ urine blood (normal is negative). All other laboratory values were normal. These findings are most compatible with

A physician asks your laboratory to begin performing thyroid-stimulating hormone (TSH) analyses on all specimens that have a free thyroxine (FT4) analysis ordered, a practice that your laboratory currently does not perform. Your laboratory typically performs TSH only on those FT4 specimens that are outside the population-based reference interval. The physician suggests using subject-based reference intervals, claiming that population-based intervals are clinically insensitive. What is the basis of this claim?

An ideal cardiac marker should be elevated in the circulation for how long following a cardiac event?

What hormone(s) are produced by the posterior pituitary?