Tamiflu was designed based on understanding how influenza virus replicates inside target cells. Which step of the viral replication cycle does this antiviral drug inhibit?

You have discovered what you think is a new herpesvirus. You have a tube of serum containing the potential virus. When you have looked at it using electron microscopy, you see what you think are herpesvirus particles, at a concentration of about 2.4 x 109 particles/ml. But this does not always equate with titer. What assay would you typically use to figure out the titer of your virus in your serum sample?

In what major way does the replication of a – strand RNA virus differ from that of a + strand RNA virus, and what key enzyme is required?

Which of the following does not represent a barrier to infection of the lung?

Pterostilbene is a molecule with antioxidant properties that is produced in a variety of different plants including almonds, berries, and grapes. Which three (3) of the following depict reasonable resonance structures of pterostilbene? Choose carefully: a penalty will be applied for each incorrect selection. Only choose answers that you are sure of; do not guess.

The neurotransmitter epinephrine, also known as adrenaline, is involved in regulating visceral functions (e.g., respiration) and plays an important role in the fight-or-flight response in many animals. Consider the structure of N-protonated epinephrine (shown below) and answer the following questions. The lowest-energy conformation of N-protonated epinephrine is stabilized by hydrogen bonding between the hydroxyl and the ammonium group. Which of the following Newman projections (A-F) represents this conformation viewed through the C1-C2 bond?   Recall that dihedral angles are measured clockwise when answering the next two questions. Consider the conformation of N-protonated epinephrine in which the aryl (Ar) substituent and the ammonium group are eclipsed. What is the dihedral angle between hydroxyl group and ammonium group in this conformation? What is the dihedral angle between the aryl (Ar) substituent and the ammonium group in Newman structure B? Do Newman structures A and C represent conformational isomers?

For each of the acid-base reactions (A-C) below, determine whether the equilibrium would lie to the left or to the right. Reaction A: Reaction B: Reaction C:

Rank the following ions in terms of the equilibrium constant Keq for their reaction with HCl. smallest Keq < < < largest Keq

Classify each of the following as either a Brønsted-Lowry acid, Lewis acid, or neither. A: B: C: D:

What is the mechanism of action of amantadine?