A 25-year-old woman with a history of bipolar affective disorder is experiencing an episode of mania. She currently takes lithium and serum levels are determined to be in range.  Which of the following pharmacological strategies would be MOST appropriate for her, alongside psychological support?

A 46-year-old male is suffering from chronic neuropathic pain following a mechanical back injury 2 years ago. He has been referred to the pharmacist led pain management clinic to review his medications.  Which of the following would NOT be an appropriate choice of medication to initiate for neuropathic pain?

Which of the following statements is CORRECT about the Quality Control testing of patches?

You are a Pharmacist in Sunderland City Centre. A Female Patient aged fifteen (15) years of age arrives into your Pharmacy. The Patient has been issued a Prescription to treat a number of Gynaecological Issues by her GP, including the Contraceptive Pill.  Your Pharmacy Assistant has several concerns about the processing of the Prescription, including the age of the Patient. The Pharmacy Assistant suggests that you double check both the basis of the Informed Consent as well as the Patient Clinical History. a.    Which Case was the Legal Basis for the legalisation of the Informed Consent of a Mature Minor, i.e. a Patient under sixteen (16) years of age? Outline the Legal Guidelines from this Case that govern the Informed Consent of a Mature Minor.      (1.5 Marks ) b.    What is the Legal Test that governs the Standard of Care in Informed Consent? Outline briefly the Case Law which is the basis of this Legal Test.     (1.5 Marks ) c.    What are Legal Categories of Personal Information? Which Legal Action under the Common Law enables a Patient to protect his/her Confidential Information from inappropriate disclosure?      (1 Mark ) d.    Do you always have to get a Patient’s Informed Consent to share his/her Clinical Information with another Healthcare Professional such as a GP? Outline briefly the Legal Defence to a Breach of a Patient’s Confidentiality.   (1 Mark )

Section B 10 COMPULSORY Short-Answer Questions  (Total Marks 50)

 A 57-year-old woman presents to the pharmacy for advice. She has had trouble sleeping for the past three weeks. She has been going through a stressful time lately as she has recently lost her job. She is managing to go to sleep easily but is suffering from early morning waking.   What would be the MOST appropriate management for this patient?

Which of the following structures is a tricyclic antidepressant (TCA)?     

A 20-year-old student, had a seizure ‘out the blue’ 6 months ago while watching a football match on TV with friends. He had three more seizures over the next 4 months, and was referred to a consultant neurologist. After detailed examination and investigations, he has now been diagnosed with complex partial seizures.  What are partial or focal seizures?  (1 Mark) Compare and contrast the key features of simple partial epileptic seizures and complex partial epileptic seizures. (4 Marks)

Section A   50 compulsory MCQs from across the module PHA333  (Total Marks 50)    

A 19-year-old man has been diagnosed with attention deficient hyperactivity disorder (ADHD). He does not have any other medical conditions but has a history of drug abuse. The decision has been made to start pharmacological treatment for ADHD.  Which of the following options may be MOST suitable for this man?