In the failing heart, ATP production is less efficient leading to an energy deficit
In the normal heart, 90% of the ATP needed is produced throu…
In the normal heart, 90% of the ATP needed is produced through which of the following metabolic processes?
miRNAs primarily target mRNAs by inhibiting mRNA translation…
miRNAs primarily target mRNAs by inhibiting mRNA translation (rather than cleavage)
Which of the following is one of the main energy demands in…
Which of the following is one of the main energy demands in the normal adult heart?
In heart failure, increased activity of Class-I histone deac…
In heart failure, increased activity of Class-I histone deacetylases (HDACs) decreases expression genes that are involved in which of the following processes?
Alkylating agents such as cyclophosphamide or lomustine inhi…
Alkylating agents such as cyclophosphamide or lomustine inhibit DNA replication by which of the following mechanisms?
Monensin is an ionophore that causes toxicity by selectively…
Monensin is an ionophore that causes toxicity by selectively transporting which of the following ions across the membrane?
The positive inotrope pimobendan increases contractility thr…
The positive inotrope pimobendan increases contractility through which of the following mechanisms?
Phospholipase-A2 is which of the following types of venom pr…
Phospholipase-A2 is which of the following types of venom protein?
Inhibiting the mitochondrial pore is a potential therapeutic…
Inhibiting the mitochondrial pore is a potential therapeutic avenue for preventing doxorubicin cardiotoxicity