The impact of which one of these inhibitors can be revered upon addition of more substrate ?

While the oxygen bonding graph to myoglobin is hyperbolic, hemoglobin shows a sigmoidal binding curve.

What is the definition of the isoelectric point of an amino acid?

The following two compounds are……………  

How many chiral centers in Acetyl COA?  

In the context of Michaelis-Menten kinetics, which of the following statements correctly describes the relationship between the reaction velocity (V), substrate concentration , and the Michaelis constant (Km) when the substrate concentration is much greater than KmK_mKm​?

Bradykinin has the following structure:   What is the sequence of the amino acids from the N- terminal to the C- terminal in a single letter abbreviation?  

Which one of the following protein separation technique depends on the charge to mass ratio?

Ibuprofen is a widely used nonsteroidal anti-inflammatory drug (NSAID) that exhibits its therapeutic effects primarily through the competitive inhibition of cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2. These enzymes are crucial in the biosynthesis of prostaglandins, which are lipid compounds involved in mediating inflammation, pain, and fever. COX enzymes convert arachidonic acid into prostaglandin H2 (PGH2), which is then further metabolized into various other prostaglandins that promote inflammation and pain signaling. Ibuprofen competes with arachidonic acid for binding to the active site of COX enzymes, thereby reducing the formation of prostaglandins. Its competitive inhibition is reversible, meaning that it temporarily blocks the active site of the COX enzymes without permanently altering their structure. While ibuprofen inhibits both COX-1 and COX-2 isoforms, its inhibition of COX-2 is largely responsible for its anti-inflammatory and analgesic effects. However, the inhibition of COX-1 can lead to some of the common side effects associated with NSAID use, such as gastrointestinal irritation, because COX-1 is also involved in maintaining the protective lining of the stomach and regulating platelet aggregation. By inhibiting COX enzymes, ibuprofen reduces the levels of prostaglandins at sites of injury or inflammation, leading to decreased pain, swelling, and fever. This competitive inhibitory mechanism makes ibuprofen effective in treating conditions like arthritis, muscle pain, headaches, and menstrual cramps. Its relatively short half-life and reversible binding allow for flexible dosing, making it one of the most popular over-the-counter NSAIDs for managing mild to moderate pain and inflammation. The following lineweaver-Burke diagram represents the kinetic parameters of different doses of Ibuprofen,  What is an ideal description for the change in kinetic parameters induced due to Ibuprofen?        

What are Haptens and what is their role in the immunity system.