What is the mechanism of action of lumefantrine?                                                           1.        It inhibits the detoxification of the heme in the erythrocyte2.        Its metabolites produce reactive oxygen species which are fatal to the malaria parasite3.        It inhibits plasmodial dihydrofolate reductase required for the synthesis of tetrahydrofolate4.        Inhibits nucleic acid synthesis by oxidizing amoebic DNA5.        Inhibits plasmodial protein synthesis by binding to 30S ribosomal subunits

The following drug can cause anorexia                                                                                  1.        Metformin2.        Glimepiride3.        Repaglinide4.        Pioglitazone5.        Insulin

Concomitant use of the following drugs with sildenafil is potentially fatal:              1.        Lamivudine2.        Lidocaine3.        Isosorbide mononitrate4.        Omeprazole 5.        Tenofovir

The mechanism of weight gain in patients on antipsychotics relates to the following   effect:                                                                                                                                               1.        Direct effect on D2 receptors2.        Increased sensitivity to leptin 3.        H1 antagonism 4.        Prolactin suppression 5.        HT2c agonism 

The following anticancer drug is classified as an antimetabolite:                                   1.       Chlorambucil2.       Cyclophosphamide3.       Ifosfamide4.       Methotrexate5.       Melphalan

Predict the injury: What ligament is at most risk of being torn or strained when a baseball player severely hyperextends his knee while slipping on a base, (Bryce Harper, pictured to the right, recovered fully from this moderate sprain)?

Identify the function(s) of the skeletal system. (SELECT ALL THAT APPLY)

The trabeculae of spongy and woven bone are designed to withstand pressure from what direction?

Rank these joints in order from most (1), to intermediate (2), to least mobile (3). (1pt each)

What cells are bone stem cells, giving rise to bone-producing cells?