Both the respiratory and intestinal tracts are part of the mucosal immune system. One key difference between these two barrier tissues is

Which of the following contribute to dendritic cells tolerance in mucosal immunity?

Oral inoculation with rotavirus, an intestinal pathogen, induces adaptive immune responses that are initiated in gut-associated lymphoid tissue, such as mesenteric lymph nodes and Peyer’s patches. The rotavirus-specific effector T cells that are generated in this response are never found in the circulation, but home directly from the lymphoid tissue to the epithelium without ever leaving the intestinal environment.

B cell activation and differentiation ensues after HIV entry into host

Match the following gene defects with the associated primary immunodeficiency

Shigella escapes immune response by

Effector cells of the MALT are found in the following locations:

Important information can be learned by studying the immune system of female carriers of the XLA disease gene. These individuals show random X chromosome inactivation in their T cells and macrophages among other cells. This finding indicates that:

When Shigella gains access to the intestinal epithelium, which of the following apply

NFκB is a key transcription factor activated by the TLRs and NOD pathways and that induces an inflammatory response to infection.