The same haplotype block on six different homologous chromosomes from the population is shown below. The five SNPs in this block are genotyped on each chromosome; the rest of the DNA sequence (…..) is identical between the chromosomes. 1) How many different haplotypes can you see? 2) Which combination of SNPs could be used as TAG-SNPs to identify the haplotype found in in this haplotype block?
Down syndrome is a developmental disorder usually caused by…
Down syndrome is a developmental disorder usually caused by an extra 21st chromosome (Trisomy 21). In other words, most people with Down syndrome have three 21st chromosomes, rather than two. A study in 2011 examined early developmental pruning of retinal ganglion cells in the lateral geniculate nucleus in a mouse model of Down syndrome. Below is a figure from this paper: Which conclusion could you derive from this figure:
What is the genetic variation in the Huntingtin gene that ef…
What is the genetic variation in the Huntingtin gene that effects disease risk and disease severity in Huntington’s disease?
Normal Reabsorption of fluid into the capillary takes place…
Normal Reabsorption of fluid into the capillary takes place at the arterial end or venous end of the capillary?
The AV Node is the heart’s original ‘pacemaker”.
The AV Node is the heart’s original ‘pacemaker”.
___________ refers to the thickness of blood components that…
___________ refers to the thickness of blood components that resists flow, and affects vascular resistance:
Calculate Mean Arterial Pressure from a diastolic pressure o…
Calculate Mean Arterial Pressure from a diastolic pressure of 121 mm Hg and a systolic pressure of 208 mm Hg:
The closing of the semilunar valves:
The closing of the semilunar valves:
Which part of the intrinsic conduction system delays the imp…
Which part of the intrinsic conduction system delays the impulse briefly before it moves on to the ventricles (HINT–it also can act as a secondary pacemaker of the heart)?
FIND: Cardiac Output, given that EDV=266 mL; ESV=104 mL;…
FIND: Cardiac Output, given that EDV=266 mL; ESV=104 mL; and HR=110 beats per minute: