(2pts TOTAL) Many intraocular lenses (IOL, commonly known as contacts) are made up of polymethylmethacrelate (PMMA). Although advancements have been made, there is still evidence that PMMA is not entirely biologically inert. To address this one group has looked at the effects of heparin surface modification (HSM) to enhance biocompatibility of PMMA lenses. Aqueous flare is defined as the breakdown of the blood-aqueous-barrier which causes blood borne proteins and cells to leak into the space inside the eye between the iris and the cornea’s innermost surface, the endothelium. Answer the following questions below.  (0.4pts) Explain the significance of the following plot and what you have been told about aqueous flare in regard to potential immune response. *What happens, why, and how VERY BRIEFLY* (0.4pts) The following plot interrogates fibroblast adhesion to the IOL over time. An asterisk (*) represents a statistical difference. Describe the results in this figure AND their biological significance. *What happens, why, and how (type of tissue) VERY BRIEFLY* (0.4pts) The following plot interrogates foreign-body giant cell adhesion to the IOL over time. An asterisk (*) represents a statistical difference. Describe the results, why this happens, and their biological significance. (0.4pts) Based on the results in these figures, would you recommend continued production of HSM IOLs? Justify your answer. (0.4pts) Assume you decided to add foreign cells to your HSM polymer implant. Describe how the body would respond to this combinatorial (cells + synthetic biomaterial) implant. Specifically describe the sequence of events in terms of the types of inflammation and types of tissue formation.

Given the list below, which animal has a naturally large amount of sediment found in their urine? 

  For the circuit shown below, assume collector current I C Q = 4   mA I_{CQ} = 4 \, \text{mA} , β = 100 \beta = 100 (with I E ≈ I C I_E \approx I_C ​), and V B E ( on ) = 0.7   V V_{BE(\text{on})} = 0.7 \, \text{V} . The emitter resistor R E R_E ​ is given as 1   k Ω 1 \, \text{k}\Omega , as indicated. Determine the value of R 1 R_1 that ensures the circuit remains bias-stable. For this calculation, you do not need the values of R C R_C or V C E V_{CE} ​. Assume the transistor operates in the forward active region. Select the value closest to your result. find R1.jpg

For the amplifier below, assume VEB(ON)=0.7 V, β=100 (take IC=IE) and VA Early voltage is infinity. All capacitors are very large. Which one of the following is the DC load line equation for the amplifier? pnpCE.jpg

Consider the molecule:               Specify the hybridization of each carbon atom. C-1C-2C-3C-4C-5

Which industry utilized LeFlore County’s dense forests in the late 19th century?

Given a cylinder of fixed volume filled with 1 mol of argon gas, which of the following is correct? (Assume all gases obey the ideal gas law.)

Three 1.00-L flasks at 25°C and 725 torr contain the gases CH4 (flask A), CO2 (flask B), and C2H6 (flask C).In which single flask do the molecules have the greatest mass, the greatest average velocity, and the highest kinetic energy?

The hybridization of the central atom in I3– is:

An automobile tire is filled with air at a pressure of 27.0 lb/in2 at 25°C. A cold front moves through and the temperature drops to 5°C. Assuming no change in volume, what is the new tire pressure?