A 72-year-old woman comes to your clinic with complaints of fatigue, easy bruising, weight loss, and abdominal distention. Her pulse is slightly fast, and she has notable pallor and splenomegaly. Blood counts reveal anemia and thrombocytosis. You are concerned that she may have myelofibrosis.What RBC morphology would you expect to see on the peripheral blood smear if she did have significant fibrosis in the marrow?

What is the most common red cell morphologic finding in PK deficiency?

A burn patient develops leukocytosis and a “shift to the left”. Large light blue staining cytoplasmic inclusions are found near the periphery of many neutrophils.  These inclusions are probably

Patients with acute promyelocytic leukemia often have which genetic abnormality?

Calculate and interpret the absolute and relative cell counts. WBC count: 42 x 109/L Differential: 40% segmented neutrophils 15% lymphocytes 1% basophils 9% monocytes 35% atypical lymphocytes

Which AML subtype reacts positively with MPO and specific esterase, and shows evidence of t(8;21):

Heinz bodies composed of:

Which does the World Health Organization use to classify hematopoietic neoplasms?

All of the following mutations are commonly detected in cases of Esstential thrombocythemia and Primary myelofibrosis, except:

During a discussion of RBC indices, a medical technologist of Cambodian origin mentioned that she had a history of mild anemia and microcytic red blood cells noted on laboratory testing from previous routine physicals. A more recent CBC showed the following results. TEST      RESULTSWBC      9.3 x109/LRBC       5.11 x1012/LHGB      10.0 g/dLHCT       31.8%MCV      69.6 fL MCH     22.5 pg MCHC   31.0 g/dLRDW     16.5PLT        351 x109/L Differential: Within normal limits, many target cells noted. What disorder is suspected?